Age-Related Macular Degeneration (AMD)
Nov. 28, 2012 Eylea approved in Europe
One of Eylea’s key selling points will be its less frequent dosing. Bayer’s drug is given every two months after three initial monthly injections, compared to monthly Lucentis injections.
Read more: Eye drug Eylea approved in Europe
Das eine Medikament teuer und zugelassen, das andere sehr viel preiswerter, aber nicht zugelassen: Seit Jahren schwelt ein heftiger Konflikt um die Therapie bei feuchter AMD (Altersabhängige Makula-Degeneration). Entsprechend groß ist das Interesse an einer US-amerikanischen Vergleichsstudie. Das erste Ergebnis: Lucentis und Avastin wirken annähernd gleich gut.
Weiterlesen: Avastin und Lucentis Kopf an Kopf
Amerikanische Studie zeigt gleich gute Ergebnisse für Ranibizumab (Lucentis®) und Bevacizumab (Avastin®) in der Behandlung der feuchten Makuladegeneration
Weiterlesen: Pressemitteilung von DOG, RG und BVA zur CATT-Studie
Preliminary two-year safety data from the landmark CATT trial of biologic drugs for macular degeneration partially reversed conclusions from the one-year results reported last week, study leaders said in an oral presentation Sunday.
Read more: ARVO: Two-Year Safety Equal in AMD Drug Trial
Eine großangelegte randomisierte Studie konnte erstmalig belegen, dass eine Behandlung der altersbedingten Makuladegeneration (AMD) mit Ranibizumab (Lucentis) oder Bevacizumab (Avastin) zu vergleichbaren Ergebnissen führt.
Weiterlesen: Avastin und Lucentis sind gleichwertig
After one year, bevacizumab appears to be as effective as ranibizumab in improving visual acuity associated with age-related macular degeneration when administered on the same schedule, according to a study published online April 28 in the New England Journal of Medicine in advance of a presentation at the annual meeting of the Association for Research in Vision and Ophthalmology, to be held from May 1 to 5 in Fort Lauderdale, Fla.
Read more: ARVO: Age-Related Macular Degeneration Drugs Equal
Der Pharmakonzern Roche will das Medikament Lucentis weiterhin für "nasse" altersbedingte Makuladegeneration (AMD) entwickeln. Die Publikation von Daten der CATT-Studie im "New England Journal of Medicine" liefere wichtige Informationen über zwei Behandlungsformen für AMD.
Weiterlesen: Roche will Lucentis weiter für altersbedingte Makuladegeneration entwickeln
"As an organization representing more than 30 million people around the world living with age-related macular degeneration, we have been anxiously awaiting the results of the CATT study," said AMD Alliance International CEO, Narinder Sharma.
Read more: AMDAI Responds to CATT Trials Research
Eine Vergleichsstudie des US-National Eye Institute ist offenbar zu dem Ergebnis gekommen, dass die beiden Wirkstoffe Bevacizumab (Avastin) und Ranibizumab (Lucentis) in der Behandlung der feuchten AMD gleichwertig sind.
Weiterlesen: US-Studie: Avastin und Lucentis offenbar gleichwertig
A new study published online today in The New England Journal of Medicine (NEJM) shows bevacizumab (Avastin) is as effective as ranibizumab (Lucentis), the current Food and Drug Administration-approved drug for treating age-related macular degeneration (AMD).
Read more: Cheaper drug found to treat macular degeneration equally
Researchers are reporting results from the first year of a two-year clinical trial that Avastin, a drug approved to treat some cancers and that is commonly used off-label to treat age-related macular degeneration (AMD), is as effective as the Food and Drug Administration-approved drug Lucentis for the treatment of AMD.
Read more:
The first public presentation of data from the National Eye Institute's head-to-head study of Lucentis vs. Avastin in macular degeneration will take place this weekend. The Comparison of Age-Related Macular Degeneration Treatments Trial (CATT) is sure to go down as an early landmark in the era of comparative effectiveness research - though exactly how it will be remembered is less clear.
Read more: Preparing for the CATT Study: Will Makena Controversy Have an Impact?
Results of a key study comparing Roche and Novartis's eye treatment Lucentis with low doses of cancer drug Avastin will, as predicted, be presented at the ARVO medical meeting on May 1.
Read more: Head-to-head eye drug results confirmed for May 1
Results of the so-called CATT study comparing Roche (ROG.VX) and Novartis's (NOVN.VX) eye drug Lucentis with low doses of cancer treatment Avastin may be presented at a medical meeting in early May.
Read more: Lucentis vs Avastin study may feature at May 1-5 congress
The Comparisons of Age-Related Macular Degeneration Treatments Trials (CATT) is a multi-centered randomized clinical trial to assess the relative safety and efficacy of two treatments for subfoveal neovascular Age-Related Macular Degeneration (AMD), a disease that usually causes severe irreversible vision loss. CATT will be conducted in 44 clinical centers and is funded by the National Eye Institute.
Read more: CATT Study
CATT will be the first head-to-head trial of ranibizumab versus bevacizumab and is expected to return important safety and cost data
CATT is a multi-centre randomised controlled trial designed assess the efficacy of ranibizumab compared with bevacizumab therapy for the treatment of neovascular AMD.
Read more: Ranibizumab versus Bevacizumab for the Treatment of neovascular macular degeneration: CATT study
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